Manufacturing Senior Manager, Liso-cel CAR-T, Manufacturing Operations

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

At Bristol Myers Squibb we are reimagining the future of cell therapy. With our bold ambition, backed by a best-in-the-industry team and long-term commitment, we are leading the way to unlock the full promise of cell therapy as we strive to put more patients on the path to a cure. If you are ready to challenge yourself, accelerate your career, and give new hope to patients, there’s no better place than here at BMS with our Cell Therapy team.

The Senior Manager, Manufacturing provides oversight of Manufacturing Managers and Work Centered Teams operating on a 24/7 schedule to execute Cell Therapy manufacturing processes while sustaining a culture of safety, compliance, accountability, innovation, urgency, passion, and continuous improvement. This role reports to the Manufacturing Associate Director.

Shift Available:

- Saturday-Wednesday, Onsite Night Shift, 11:30 p.m. - 8 a.m.

Responsibilities:

- Ensure Manufacturing Managers and WCT members execute Cell Therapy manufacturing in compliance with cGMPs, approved SOPs, WIs, batch records, safety expectations, and ALCOA+ documentation principles.
- Maintain hands-on process expertise across unit operations, support MRB data collection, provide weekend/technical coverage as needed, and develop CAR-T manufacturing and regulatory knowledge.
- Manage production resources by tracking availability, supporting scheduling needs, maintaining records of planned/unplanned absences, and hiring talent aligned with job requirements, budget, and BMS values.
- Set priorities, establish WCT goals, monitor performance, and report metrics and progress through Tier meetings, performance reviews, site control plans, and cross-functional manufacturing forums.
- Maintain 100% on-time training compliance, ensure personnel are qualified before performing tasks, allocate time for training, and disqualify personnel from GMP tasks when compliance gaps are observed.
- Build and develop high-performing teams through recruiting, onboarding, Workday profile maintenance, performance management, recognition, coaching, regular 1:1s, career development, and timely feedback.
- Lead deviation troubleshooting and quality record ownership as BPO/BTA, ensure clear and timely deviation entries, monitor metrics, identify repeat causes, drive on-time closure, and prevent recurrence through continuous improvement.
- Participate in CAPAs, Change Controls, and projects; define or own actions for Manufacturing and ensure implementation before due dates.
- Control expenses within area of influence, including overtime, supplies, and travel/expense costs.
- Model leader behaviors by maintaining shopfloor presence, conducting Gemba/Go & See activities, using tiered management, visual management, coaching kata, root-cause problem solving, risk escalation, and cross-functional collaboration.

Knowledge & Skills:

- Extensive knowledge of EHS, cGMPs, biotechnology principles, manufacturing systems, lean manufacturing, and regulated operations; Green Belt certification preferred.
- Strong communication, adaptability, strategic leadership, team selection, and people management skills.

Minimum Requirements:

- Bachelor’s degree in a related field preferred, or equivalent work experience; advanced degree preferred.
- 7+ years of relevant manufacturing experience, including at least 5 years of leadership experience managing direct reports.

Working Conditions:

- Role requires intermittent walking, sitting, standing, computer/documentation use, sufficient vision/hearing, ability to lift 25 pounds, and work in laboratories, cleanrooms, and controlled or restricted areas.
- PPE and cleanroom garments may be required.
- Exposure may include human blood components, reagents, chemicals, sanitization agents, and strong magnets.
- Restricted areas may prohibit makeup, gum, nail polish, food, cell phones, tablets, or outside materials.

We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.

Compensation Overview:
Summit West - NJ - US: $119,102 - $144,324


The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits:

Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).

U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.

Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.

Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.

U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to  [email protected] . Visit  careers.bms.com/eeo-accessibility  to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only:  If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:  https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at  https://careers.bms.com/fraud-protection .

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If this posting is missing required information required by local law or incorrect, contact BMS at  [email protected] with the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1606426 : Manufacturing Senior Manager, Liso-cel CAR-T, Manufacturing Operations