Temporary Research Technician B

POSITION RESPONSIBILITIES

The person will:

- Perform a moderate number of simple or moderate technical procedures;

support basic and disease-focused studies on the dynein–dynactin–JIP3 (DDJ) motor complex;

- recombinant protein expression and purification,

- preparation and characterization of wild-type and disease-associated motor complexes and tweezers based forced measurement;

- assist with molecular biology, biochemical assays

- assist with maintenance of lab reagents;

- document and present research findings

- Require occasional guidance;

- Occasionally be responsible for ordering routine supplies;

- Rarely modify technical procedures;

- Rarely train other lab members;

- Rarely guide other lab members;

- A simple / limited understanding of scientific literature and the research goals and rationale is required;

- Occasionally analyze data;

- Rarely interpret data

This position is only available for one year.

QUALIFICATIONS

Bachelor's Degree in Bioengineering, Biophysics or Biochemistry or equivalent skills and related experience, and zero to two years of related experience.

## Salary Verbiage
In compliance with NYC's Pay Transparency Act, the hourly rates for this are listed below. This rate is based on the 1199 bargaining unit contract.

## Hiring Rate
$28.72

## Post Probationary Rate
$29.25

## Job Rate
$30.47

## Minimum Salary Range
USD $28.72/Hr.

## Maximum Salary Range
USD $28.72/Hr.

ABOUT US

The laboratory of Dr. Arne Gennerich is seeking a highly motivated research technician to support basic and disease-focused research on intracellular transport and its role in neurodevelopmental disorders. The work is focused on the neuronal dynein–dynactin–JIP3 (DDJ) motor complex, which powers long-distance retrograde transport in axons, and on understanding how this transport machinery adapts to changing cellular demands and is disrupted by disease-causing mutations. We employ protein biochemistry, molecular biology, quantitative single-molecule fluorescence microscopy, and optical tweezers-based force measurements to define the molecular mechanisms that regulate DDJ transport and to determine how mutations in DYNC1H1 (dynein) and MAPK8IP3 (JIP3) impair motor function. These studies aim to establish genotype–mechanism–phenotype relationships that advance our understanding of neurodevelopmental disease and provide a foundation for mechanism-based therapeutic strategies.