Senior Real World Data Scientist

This is what you will do:

The Epidemiology and   Real ‑ World   Science team in Alexion–AstraZeneca’s Rare Disease Unit accelerates patient access to innovative medicines by advancing the scientific use of  Real World   Data (RWD) . In this role, you will apply RWD to support the rare disease portfolio, aligned with  AstraZeneca  best practices and standards. Building on AstraZeneca’s strong  Real World   Evidence (RWE)  foundation and internal data assets, the team is expanding through a dedicated  Real World Data Science  capability.

Successful candidates will tackle challenging problems with innovative methods to deliver  Real World Insights and Evidence  for stakeholders in  Clinical Development ,  Regulatory , and  Patient Safety . The ideal candidate is a curious,   self ‑ directed   learner with a proven record of deriving value from routinely collected healthcare or observational data, delivering health analytics across Public Health, Pharmaceutical R&D, Commercial/Payer, and Patient Safety.

You will provide   methods   expertise ,   lead   and support analyses of RWD, and guide study design, data source selection, and best practices in RWD   utilization , emphasizing patient safety. You will also help shape Alexion/AZ’s RWS data strategy by supporting due diligence on data   vendors and   offering informatics support for Therapeutic Area data acquisitions.

You will   be responsible for :

- Deliver/Implement and support advanced secondary analyses of data from EMR, claims and primary observational data required by Therapeutic Area (TA) RWE strategies

- Comfortable working in a rapid analytics environment alongside stakeholders to ideate appropriate/impactful analysis along with implementation

- Provide clear technical input,   options   and directions to support strategic decisions made by AZ observational study teams on study design, data partner   selection   and best practices in RWE data   utilization

- Monitor work performed by contract personnel and vendors

- Maintain a strong insight into the capabilities of potential external partners in RWE, especially for US and emerging markets.

- Demonstrate best practice in Real World Data Science across multiple domains, and/or stakeholder groups.

You will need to have:

- Minimum of   master’s degree in   Biostatistics, Epidemiology, Public Health,   Statistics, Mathematics, Data Science, or related field with at least 3 years in the pharmaceutical industry, biotechnology, or consulting environment.

- The duties of this role are   generally conducted   in an office environment.  As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

We would prefer for you to have:

- This is a   hands-on   role – so be excited to code!

- Enthusiastic about building on and learning new methods and ways to use real world data to change the practice of medicine

- Demonstrated ability to build long-term relationships with   stakeholders,   understand relevant scientific/business challenges at a deep   level   and translate into a programme of data science activities to deliver value to the business

- Hands-on experience with EMR, disease registries, and/or insurance claims databases

- Experience   with in   clinical data standards, medical terminologies and controlled vocabularies used in healthcare data and ontologies (ICD9/10/SNOMED)

- Experience in supporting pharmacoepidemiology studies with proven   track record   of advancing approaches with   statisti cs/machine learning/data science

- Ability to lead & handle multi-disciplinary data science projects

- Proficient in SQL

- Proficient in at least one of R, Python

Date Posted
18-Sept-2026

Closing Date
01-Oct-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.