Fermentation Technician IV

Job Title: Fermentation Technician Night Shift Job Description The Fermentation Technician Night Shift supports upstream biologics manufacturing operations within a GMP-regulated commercial facility. This role focuses on fermentation and upstream processing activities, including hands-on operation of bioreactors, monitoring manufacturing processes, and executing batch production in support of a 24/7 manufacturing operation. The technician ensures strict compliance with quality, safety, and regulatory requirements while contributing to reliable and efficient production on the night shift. Responsibilities

- Execute fermentation manufacturing operations in accordance with current Good Manufacturing Practices (cGMP), standard operating procedures, and batch record requirements.
- Set up fermentation and upstream processing equipment, including bioreactors and single-use systems, to support production activities.
- Monitor fermentation processes and manufacturing operations, including tracking critical process parameters and responding to alarms or process changes.
- Perform in-process sampling and testing activities, including pH measurements, conductivity checks, and visual inspections to ensure process control and product quality.
- Support harvest operations and upstream production execution, following defined procedures and safety guidelines.
- Execute validation protocols in accordance with approved procedures and GMP requirements to qualify equipment, processes, and systems.
- Utilize manufacturing systems and process control platforms, including Distributed Control Systems (DCS) and Manufacturing Execution Systems (MES), to operate equipment and record process data.
- Perform takeouts, identity checks, material transactions, and production activities within electronic manufacturing systems and electronic batch records.
- Carry out cleaning and sanitization activities, including Clean-in-Place (CIP) and Steam-in-Place (SIP) processes, to maintain equipment and facility cleanliness.
- Maintain accurate, complete, and timely GMP documentation for all manufacturing activities, including logs, batch records, and deviation reports.
- Identify, document, and communicate deviations, and initiate maintenance work orders when necessary to ensure equipment reliability and process integrity.
- Support manufacturing investigations, deviations, and continuous improvement initiatives by providing process information and participating in problem-solving activities.
- Collaborate with cross-functional teams to ensure safe, compliant, and efficient production operations across the manufacturing facility.
- Participate in shift turnover activities and effectively communicate process status, issues, and priorities to incoming teams on the rotating night shift.
- Perform other related duties as assigned to support overall manufacturing and operational goals.

Essential Skills

- Strong written and verbal communication skills to document activities clearly and communicate effectively with team members.
- Knowledge of cGMP regulations and safety requirements applicable to biologics and pharmaceutical manufacturing environments.
- Ability to work effectively in a team environment and collaborate with cross-functional groups.
- Strong time management skills and attention to detail to execute complex manufacturing processes accurately.
- Ability to identify and document deviations and initiate maintenance work orders when necessary.
- Ability to exercise sound judgment, work independently, and solve problems in a manufacturing environment.
- Ability to support a 24/7 manufacturing facility and work a rotating night shift schedule.
- Ability to perform fermentation, sampling, and upstream processing activities, including operation of bioreactors and single-use systems.
- Minimum of 4+ years of experience in a cGMP manufacturing environment with a High School Diploma/GED; OR 2+ years of cGMP manufacturing experience with an Associate degree in Life Sciences, Engineering, or a related technical discipline; OR a Bachelors degree in Life Sciences, Engineering, or a related technical discipline; OR equivalent military training or experience.

Additional Skills & Qualifications

- High School Diploma/GED, Associate degree, Bachelors degree in Life Sciences, Engineering, or a related technical discipline, or equivalent military training or experience.
- Experience supporting fermentation, microbial manufacturing, or other upstream bioprocessing operations.
- Experience working within a GMP-regulated biologics, biotechnology, or pharmaceutical manufacturing environment.
- BioWork certification.
- Familiarity with automated manufacturing control systems, such as Distributed Control Systems (DCS) and Manufacturing Execution Systems (MES).
- Experience with electronic batch records and electronic manufacturing systems.
- Experience operating bench-scale or large-scale bioreactors and associated upstream equipment.
- Comfort working in a structured, procedure-driven environment with strict documentation and compliance expectations.

Work Environment This position is based at an onsite manufacturing facility that operates 24/7 to support commercial biologics production. The role is assigned to the night shift on a 2-2-3 rotating schedule, requiring flexibility to work nights, weekends, and holidays as needed. The technician works in GMP-regulated production areas with automated process control systems, bioreactors, single-use technologies, CIP/SIP equipment, and electronic manufacturing systems. The environment may involve temperature-variable conditions and requires the use of personal protective equipment, including respiratory protection when necessary. The role is physically active and involves standing for extended periods, performing repetitive tasks with hands, wrists, and fingers, bending, pushing, pulling, reaching, lifting materials up to 33 pounds, and ascending and descending ladders to access manufacturing equipment. Work is performed in a clean, safety-focused setting with established procedures and a culture that emphasizes teamwork, compliance, and continuous improvement. The assignment is expected to last a minimum of 6 months, with preference for candidates interested in a 12+ month engagement, and includes an onsite panel interview as part of the hiring process.
Job Type & Location
This is a Contract position based out of Raleigh, NC.
Pay and Benefits
The pay range for this position is $35.00 - $43.00/hr. Individual compensation offered for this position within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, geographic location, internal equity, and other pertinent job-related factors. Eligibility requirements apply to some benefits and may depend on your job
classification and length of employment. Benefits are subject to change and may be
subject to specific elections, plan, or program terms. If eligible, the benefits
available for this temporary role may include the following:

Medical, dental & vision
Critical Illness, Accident, and Hospital
401(k) Retirement Plan Pre-tax and Roth post-tax contributions available
Life Insurance (Voluntary Life & AD&D for the employee and dependents)
Short and long-term disability
Health Spending Account (HSA)
Transportation benefits
Employee Assistance Program
Time Off/Leave (PTO, Vacation or Sick Leave)
Workplace Type
This is a fully onsite position in Raleigh,NC.
Application Deadline
This position is anticipated to close on Sep 30, 2026. About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service.

The company is an equal opportunity employer and will consider all applications without
regard to race, sex, age, color, religion, national origin, veteran status, disability,
sexual orientation, gender identity, genetic information or any characteristic protected
by law.

If you would like to request a reasonable accommodation, such as the modification or
adjustment of the job application process or interviewing process due to a disability,
please email [email protected] for other accommodation options.

San Francisco Fair Chance Ordinance:
Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the
city and county of San Francisco, we will consider for employment qualified applicants
with arrest and conviction records.

Massachusetts Lie Detector:
It is unlawful in Massachusetts to require or administer a lie detector test as a
condition of employment or continued employment. An employer who violates this law
shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI):
We may use Artificial Intelligence (AI) to support parts of our hiring process,
including sourcing, screening, and evaluating candidates. AI helps assess applications
and qualifications, but final decisions are made by our hiring team. By applying, you
acknowledge and agree that your application may be reviewed using AI tools.