Biologist - New Approach Methodologies (NAMs)

Battelle delivers when others can’t. We conduct research and development, manage national laboratories, design and manufacture products and deliver critical services for our clients—whether they are a multi-national corporation, a small start-up or a government agency.

We recognize and appreciate the value and contributions of individuals from a wide range of backgrounds and experiences and welcome all qualified individuals to apply.

## Job Summary

Battelle is seeking a Senior Scientist to lead and support the development, application, and evaluation of New Approach Methodologies (NAMs), especially complex in vitro models including microphysiological systems (MPS) and other human-relevant non-animal testing platforms. This role will provide growing technical leadership in the use of organoids, organ-on-chip systems, advanced in vitro models, omics technologies, and computational approaches for chemical safety assessment, biomedical research, and product development.

The Biologist III will independently lead defined technical workstreams and contribute to the scientific direction, design, execution, and interpretation of complex research studies. Working with multidisciplinary teams of  biologists, engineers, computational scientists, and regulatory specialists, this individual will help translate emerging human-relevant technologies into robust, reproducible, and decision-ready tools.

## Responsibilities

- Lead the design, execution, analysis, interpretation, and reporting of complex studies involving NAMs, MPS, organoids, organ-on-chip systems, and other physiologically relevant in vitro models.
- Serve as a technical lead for defined project workstreams, ensuring studies are scientifically sound, appropriately documented, on schedule, and aligned with project objectives.
- Develop, optimize, implement, and evaluate MPS and advanced in vitro platforms for toxicology, safety assessment, discovery, or translational research applications.
- Design studies to assess model performance, reproducibility, biological relevance, applicability domain, and fit-for-purpose use in specific decision contexts.
- Lead troubleshooting and method-development activities; recommend improvements to experimental designs, assay workflows, analytical approaches, and platform operations.
- Integrate MPS findings with complementary datasets, including conventional in vitro data, omics results, computational models, exposure data, and available in vivo or clinical reference data.
- Support development of translational strategies, including in vitro-to-in vivo extrapolation and interpretation of human-relevant model outputs for safety and efficacy questions.
- Prepare and review study protocols, technical reports, project plans, data packages, standard operating procedures, and client-facing deliverables.
- Provide technical input for project proposals, statements of work, budgets, and presentations to internal and external stakeholders.
- Mentor junior staff in laboratory techniques, experimental planning, data interpretation, scientific documentation, and safe laboratory practices.
- Collaborate with internal and external partners, including academic institutions, industry organizations, and government agencies.
- Monitor and summarize relevant scientific, technical, and regulatory developments related to NAMs, MPS, organ-on-chip systems, and human-relevant toxicology.
- Contribute to peer-reviewed publications, technical reports, conference presentations, and scientific working groups.
- Maintain high standards for laboratory safety, quality, scientific integrity, data traceability, and project documentation.

## Key Qualifications

- Bachelor’s degree in related field with 5 years of experience or master’s degree in related field with 2 years of experience or PhD; or an equivalent combination of education and or experience in a related field.
- Demonstrated scientific expertise in one or more relevant areas, such as: Microphysiological systems, organ-on-chip technologies, or perfusion-based cell-culture platforms
- Organoids, 3D cell culture, co-culture, primary-cell, stem-cell, or other advanced in vitro models
- Toxicology, safety assessment, mechanistic biology, or pharmacology
- Tissue engineering, biomedical engineering, or model development
- Computational toxicology, bioinformatics, QSAR, machine learning, or predictive modeling
- Omics technologies, including transcriptomics, metabolomics, proteomics, or integrated data analysis

- Demonstrated ability to independently design and execute research studies, analyze and interpret results, troubleshoot technical challenges, and develop sound scientific conclusions.
- Experience preparing high-quality scientific reports, technical documentation, manuscripts, presentations, or client deliverables.
- Ability to lead assigned technical workstreams, manage priorities and timelines, and coordinate effectively with interdisciplinary project teams.
- Strong written, verbal, and interpersonal communication skills.
- Applicants for this position must be a U.S. citizen and possess the ability to obtain a government security clearance.

## Preferred Qualifications

- Hands-on experience developing, operating, optimizing, or qualifying MPS, organ-on-chip, or other advanced human-relevant test platforms.
- Experience applying advanced in vitro models to regulatory, pharmaceutical, chemical, consumer-product, or biomedical research questions.
- Familiarity with assay development, method qualification, validation principles, reproducibility assessments, or cross-site method-transfer studies.
- Experience integrating biological data with computational models, omics datasets, or translational modeling approaches.
- Working knowledge of regulatory science and the evolving use of NAMs by FDA, EPA, NIH/NICEATM, OECD, or comparable organizations.
- Record of scientific contributions through peer-reviewed publications, conference presentations, external collaborations, patents, technical reports, or successful project delivery.
- Experience mentoring junior scientists, research associates, interns, or students.

## Compensation Data

Battelle is committed to fair and equitable compensation practices. The salary range for this role is $81,600 - $116,300 per year, in addition to our comprehensive benefits package. A candidate’s salary is determined by various factors, including but not limited to education, relevant work experience, skills, and certifications. Salary ranges may vary based on geographic location and market conditions.

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Benefits: Live an Extraordinary Life
We care about your well-being, not just on the job. Battelle offers comprehensive and competitive benefits to help you live your best life.

- Balance life through a compressed work schedule : Most of our team follows a flexible, compressed work schedule that allows for every other Friday off—giving you a dedicated day to accomplish things in your personal life without using vacation time.
- Enjoy enhanced work flexibility, including a hybrid arrangement:  You have options for where and when you work. Our Together with Flexibility model allows you to work 60% in-office and 40% remote, with Monday and Tuesday as common in-office days, dependent on team and position needs .
- Take time to recharge : You get paid time off to support work-life balance and keep motivated.
- Prioritize wellness : Stay healthy with medical, dental, and vision coverage with wellness incentives and benefits plus a variety of optional supplemental benefits.
- Better together : Coverage for partners, gender-affirming care and health support, and family formation support.
- Build your financial future : Build financial stability with an industry-leading 401(k) retirement savings plan. For most employees, we put in 5 percent whether you contribute or not, and match your contributions on top of that.
- Advance your education : Tuition assistance is available to pursue higher education.

A Work Environment Where You Succeed
For brilliant minds in science, technology, engineering and business operations, Battelle is the place to do the greatest good by solving humanity’s most pressing challenges and creating a safer, healthier and more secure world.

You will have the opportunity to thrive in a culture that inspires you to:

- Apply your talent to challenging and meaningful projects
- Receive select funding to pursue ideas in scientific and technological discovery
- Partner with world-class experts in a collaborative environment
- Nurture and develop the next generation of scientific leaders
- Give back to and improve our communities

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Vaccinations & Safety Protocols

Battelle may require employees, based on job duties, work location, and/or its clients’ requirements to follow certain safety protocols and to be vaccinated against a variety of viruses, bacteria, and diseases as a condition of employment and continued employment and to provide documentation that they are fully vaccinated. If applicable, Battelle will provide reasonable accommodations based on a qualified disability or medical condition through the Americans with Disabilities Act or the Rehabilitation Act or for a sincerely held religious belief under Title VII of the Civil Rights Act of 1964 (and related state laws).

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Battelle is an equal opportunity employer.  We provide employment and opportunities for advancement, compensation, training, and growth according to individual merit, without regard to race, color, religion, sex (including pregnancy), national origin, sexual orientation, gender identity or expression, marital status, age, genetic information, disability, veteran-status veteran or military status, or any other characteristic protected under applicable Federal, state, or local law. Our goal is for each staff member to have the opportunity to grow to the limits of their abilities and to achieve personal and organizational objectives. We will support positive programs for equal treatment of all staff and full utilization of all qualified employees at all levels within Battelle.

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The above statements are intended to describe the nature and level of work being performed by people assigned to this job. They are not intended to be an exhaustive list of all responsibilities, activities and skills required of staff members. No statement herein is intended to imply any authorities to commit Battelle unless special written permission is granted by Battelle's Legal Department.

For more information about our other openings, please visit www.battelle.org/careers