Global Pricing & Access Lead, Rare Neurology

Alexion PharmaceuticalsBarcelona, CataloniaHybrid, On-siteFull-timePrincipal, 12–15+ yearsListed 7 hours ago

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About this role

Location : Barcelona - Spain (3 days working from the office and 2 days working from home)

At  Alexion, AstraZeneca Rare Disease , this role offers the opportunity to shape access for transformative medicines in areas of high unmet need and make a meaningful impact for patients living with   rare neurological diseases . You will operate in a highly visible, strategic position with broad cross-functional exposure, leading portfolio-level market access, pricing, and reimbursement strategy across key markets, with a particular focus on the  NMOSD  indication. This is an opportunity for an experienced market access leader to influence critical launch and lifecycle decisions, navigate complex payer environments, and play a central role in advancing our ambition within  Neurology .

What   you’ll   will   do:

Join a highly valued, strategic team that is fundamental to realizing the potential of our life-changing medicines. Through our work, AstraZeneca   is able to   ensure that appropriate access is provided to our transformative therapies.

Alexion, AstraZeneca Rare Disease’s  Global Value Access and Pricing ( GVAP ) team is seeking a qualified  Director  to join a dynamic and growing team, with responsibility for  Neurology  indications, including near-term new product launches and label expansions.

As a key member of the   GVAP   team, you will help shape and execute global value, access, and pricing strategies across the   Neurology portfolio   in selected key EU markets , with   particular strategic   focus on the   NMOSD indication   and its lifecycle management

This is a strategic role that leverages your understanding and application of global healthcare and health technology assessment ( HTA ) systems, competitive insights, and clinical knowledge to shape market access, pricing, and reimbursement success for critical product launches and indications.

The ideal candidate for this role will have deep expertise in global payer,  HTA , and reimbursement ecosystems, with a strong track record of driving market access, pricing, and reimbursement success within  rare diseases and Neurology .

You will be responsible for:

Value

- Lead and drive cross-functional development of a clear, differentiated value proposition for  NMOSD , while influencing without authority and navigating complex organizational systems.

- Collaborate with cross-functional teams to ensure that evidence generation plans and real-world evidence ( RWE ) are incorporated effectively to deliver a comprehensive value proposition, reduce uncertainty for payers, and optimize patient access. This includes securing timely country input on endpoints and evidence generation plans in priority target countries.

- Provide support to the  GMMA Commercial  team to advance  NMOSD lifecycle management (LCM)  through governance milestones focused on market access potential, evidence, and  target product profile (TPP)  requirements.

Access

- Lead   development of   global market access and pricing strategies - activities   and   support implementation   in close partnership with country access representatives   of   assigned countries

- Lead the assessment of pricing and reimbursement ( P&R ) risks and opportunities, and the implementation of corresponding mitigation actions specific to  Neurology .

- Create and roll out strategic value, access, and pricing communication tools and materials for  NMOSD  to support local  P&R  submissions and negotiations, such as pricing frameworks, negotiation strategies, and toolkits, in alignment with the enterprise-wide launch framework.

- Lead the update of the global reimbursement dossier for  NMOSD  and the overall cross-functional market access readiness plans for  Neurology , in close collaboration with key countries and support functions ( HEOR, Medical, and Commercial ).

- Represent the  GVAP  perspective and strategy across various cross-functional teams, including the  Global Value Sub-Team  and  Global Launch Team , and provide updates and guidance to local teams as needed.

- Own the monthly   Neurology   payer working group to share the latest evidence and drive best practice sharing across countries.

- Understand and incorporate the   patient   perspective on the   disease, and   recommend strategies that support the   patient   voice in key payer negotiations.

Pricing

- Support the development of   the   Neurology   pricing strategy.

- Conduct payer and value assessments to identify key market-specific P&R drivers and barriers, develop differentiated value propositions, and inform evidence generation plans, regulatory strategy, and development decisions.

- For the top EU Neurology markets, lead and co-create market-level P&R strategies and support P&R submissions and negotiations to drive positive outcomes.

- Review P&R cases submitted by   markets, and   support markets in maintaining value while unlocking local access   working i n close partnership with country access representatives and /or access International shared markets   GVAP   team for relevant countries.

- Offer critical strategic input to inform access and pricing assumptions, enabling accurate, market-driven LTP assumptions.

- Communicate effectively with GMMA senior leadership and other key stakeholders, particularly in relation to   Neurology launches and NMOSD LCM P&R strategy.

You will need to have:

- Demonstrate d   leadership and   the   ability to take initiative and consistently deliver high-quality work   in the context of rare   diseases evidence , where there is greater   uncertainty and   competiiton .

- The ability   to   c ommunicate effectively   and transla te   science into compelling   payer value story benefits   for   Alexion   leadership and other identified stakeholders ,   including close collaboration   with   local market access colleagues and the Commercial Launch Excellence function.

- Experience   developing   evidence-based innovative value solutions,   for example   through working with local payers in   the   EU or commercial customers in the US.

- A r elevant   g raduate degree , such as a   PhD, PharmD,   B iomedical   S cience s , business, or economics   qualification.

- Highly specialized rare disease   and / or N eurology   market access experience .

- More than 6 years of r elevant drug development and/or commercialization experience within the pharmaceutical/medical industry .

- Knowledge of the needs and expectations of national and regional payers, insurers, and commercial customers in our strategic markets .   Knowledge and experience in key   cost-effectiveness   markets , such as the   UK, Canada and   the   Nordics ,   is preferred.

- The duties of this role are generally conducted in an office environment.  As is typical of an office-based role, employees must be able, with or without accommodation ,   to   use a computer; engage in communications via phone, video, and electronic messaging; engage in problem - solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

Date Posted
20-oct-2026

Closing Date
03-nov-2026

Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact [email protected] . Alexion participates in E-Verify.