Research Scientist, Hematology & Oncology

The Department of Medicine, Division of Hematology & Oncology, at the University of Virginia seeks a Full-time Research Scientist to join the research team within the laboratory of Dr. Charles E. Chalfant. The start date of this position is as soon as possible. The position will be under the supervision of Dr. Charles E. Chalfant.

The Chalfant laboratory has a strong track-record of extramural funding and currently has multiple extramural grants from both the National Institutes of Health and the Veterans Administration. These grants focus on advancing two specific molecular mechanisms, RNA splicing and lipid signaling, as they relate to cancer, cardiovascular disease, wound healing, infectious disease, and diabetes. The goal is to identify key mechanisms dysregulate in these diseases that can be precisely targeted to better clinical outcomes. The laboratory also has the goal of therapeutic development to these targets.

Responsibilities inlcude:

- Serve as Project Lead for NSCLC and Wound Healing projects
- Oversight of all vertebrate animal studies and IACUC compliance in the research group.
- Develop and undertake experimental approaches in GEMM studies for the induction of tumorigenesis
- Oversight of biostatistics and bioinformatics for the laboratory.
- Develop and undertake experimental approaches in acute and chronic wound healing.
- Oversight of laboratory ordering
- Training laboratory personnel in these areas of research

The ideal candidate should possess substantial knowledge and skills to foster innovative ideas and interests in splicomics and wound healing with a solid track-record of research productivity during their PhD and postdoctoral training. Background in molecular biology (e.g., CRISPR/Cas9, lentivirus, adenovirus), lipid signaling, lipidomics, or RNA splicing as well as training/mentoring others is a plus. Excellent organizational and communication skills (both written and verbal) are required as is an ability to work independently and cross-culturally in diverse environments. . The candidate will be fully funded by funds from grants to Dr. Chalfant from the National Institutes of Health. It is expected that through expansion of research ideas in the aforementioned research areas, the candidate will develop additional skills, aid in writing grants, and construct/present research papers.

This position is 100% grant funded and is already included in the FY26 budget, and the Chalfant laboratory is dedicated to diversity in science, and applications from underrepresented minorities are welcome.

The position is located in Charlottesville, VA.

QUALIFICATIONS

Requires a doctoral degree, preferably a PhD, MD or equivalent degree in Biochemistry, Molecular Biology, Immunology, or related field. A master's degree with significant experience may also be accepted. A minimum of 6-8 years of experience is preferred with strong proficiency in wound healing, manuscript preparation, hands-on animal experiments, mouse colony maintenance, IACUC protocol construction and modification, UVA ordering systems (or equivalent), training of laboratory personnel, biostatistics, and splicomic bioinformatics.

PHYSICAL DEMANDS

This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings, and programs.

Salary will be commensurate with education and experience. This is an exempt-level, benefited position. Learn more about UVA benefits .

Initial appointments and reappointments to these positions may be made in increments of one to three years, contingent upon satisfactory performance and the availability of funding. This position is based in Charlottesville, VA, and must be performed fully on-site.

About UVA and the Community

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Additional Requirements

Background checks and pre-employment health screenings will be conducted on all new hires prior to employment.

How to Apply

Please apply online , by searching for requisition number R0089074. Complete an application with the following documents:

- Resume
- Cover Letter
- Contact information for three professional references

Upload all materials into the resume submission field. You can submit multiple documents into this one field or combine them into one PDF.   Applications without all required documents will not receive full consideration.

Internal applicants: Search and apply for jobs on the UVA Internal Careers website .

Contact

For questions about the application process, please contact Jeremy Brofft, Senior Academic Recruiter at [email protected] .

The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities. Learn more about UVA’s commitment to non-discrimination and equal opportunity employment .