Sr. Director, Launch Excellence & Operations

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of  PRAME , a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest  PRAME  franchise with the most  PRAME  indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?

- Innovative Environment:  Help to pioneer advancements in cancer immunotherapy.

- Collaborative Culture:  Be part of a diverse team dedicated to your professional growth.

- Global Impact:  Contribute to therapies that make a lasting impact on patients globally.

Role Overview

The Senior Director, Launch Excellence & Operations serves as a strategic partner and deputy to the VP, Launch Excellence, Strategy & Operations, helping shape and execute Immatics' commercial launch strategy. This highly visible role sits at the center of launch planning, governance, and operational readiness, ensuring cross-functional alignment and execution as the organization prepares for commercialization.

The successful candidate will lead integrated launch planning, support the Launch Readiness Review (LRR) process, and establish the operating rhythms, governance, and performance management frameworks necessary to drive launch success. This individual will operate seamlessly between strategy and execution, translating insights into action, guiding critical business decisions, and creating clarity in a dynamic and evolving environment.

Reports to: Vice President, Launch Excellence, Strategy & Operations

Location: US, Fully Remote

Salary Range: $250,000 - $290,000

Basic Qualifications:

- Bachelor’s degree in life sciences, business, engineering, or a related field with 15+ years of relevant experience OR

- MBA / advanced degree (MBA, PhD, MD, or equivalent) with 12+ years of relevant experience A combination of top-tier strategy consulting experience and in-house biopharmaceutical commercial strategy, commercial operations, or launch leadership experience.

Preferred Qualifications:

- 5+ years in oncology; direct experience with TCR, CAR-T, or TIL cell therapies, including a first wave of commercial launch strongly preferred

- Demonstrated ownership of commercial launch strategy or launch readiness — including launch planning, cross-functional governance, milestone and risk management, and readiness tracking through to launch.

- Knowledge of personalized manufacturing and vein-to-vein logistics, including manufacturing slot allocation and patient journey management.

- Understanding of the melanoma treatment landscape, therapeutic decision-making, and patient access barriers.

- Working knowledge of the cell therapy operational value chain — treatment center authorization, apheresis scheduling, chain of identity / chain of custody, and product delivery.

- Experience standing up launch governance, a launch readiness review process, or a commercial PMO from scratch.

- Familiarity with digital launch excellence tools and analytics.

- Experience scoping and managing external consultants, agencies, and analytics vendors.

- Proven ability to drive strategic decision-making across functions without direct authority: framing the decision, assembling the analysis, aligning stakeholders, and driving the issue to closure.

- Exceptional executive communication, influencing, and synthesis skills; able to distill complex, ambiguous cross-functional situations into a clear recommendation

- Strong strategic planning and operational execution skills.

In this role you will:

Launch Strategy & Commercial Planning

- Partner with the VP to develop and execute an integrated launch strategy, roadmap, and commercial playbook.

- Lead strategic evaluations and business cases for critical commercial decisions, capabilities, and growth opportunities.

- Continuously refine launch strategy based on market, competitive, regulatory, and operational insights.

- Develop executive recommendations and materials for senior leadership and key governance forums.

Launch Governance & Cross-Functional Integration

- Drive cross-functional alignment, decision-making, and accountability through the Launch Readiness Review (LRR) process.

- Co-own launch readiness planning, including critical milestones, dependencies, risks, and mitigation strategies.

- Establish and maintain operating rhythms, governance processes, and communication forums that support launch execution.

- Facilitate resolution of complex cross-functional issues and ensure timely escalation of key decisions.

Operational Readiness & Cell Therapy Operations Performance

- Build and monitor performance frameworks across the end-to-end cell therapy patient journey.

- Partner with operational teams to identify and address patient funnel attrition, process bottlenecks, and execution risks.

- Provide commercial leadership for systems, analytics, and reporting capabilities that enable launch readiness and operational excellence.

- Develop scalable processes and performance metrics to support successful commercialization.

Travel Requirements:

- Up to 20% travel to support cross-functional team meetings, treatment center engagement, advisory boards, congresses, and launch activities, including periodic travel to Immatics US in Stafford, TX

Qualified candidates will participate in a structured interview process, which includes:

- An initial recruiter phone screen (conducted via video)

- Interviews with the hiring leader and other key stakeholders (via video)

- A final-stage interview

What do we offer?

At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics

Comprehensive Benefits :

- Competitive rates for Health, Dental, and Vision Insurance

- 4 weeks of vacation, granted up front each year and prorated for first and last year of employment.

- 12 company paid holidays

- 7 days of sick time

- 100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars

- 100% employer-paid short- and long-Term disability coverage

- 401(k) with immediate eligibility and company match. The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.

- Partially paid parental leave for eligible employees.

- Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.

Equal Employment Opportunity

We are an equal opportunity employer and are committed to building a diverse and inclusive workplace.  We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.

Reasonable Accommodations

We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances.  If you require assistance or accommodation during the application or interview process, please contact us at  [email protected] .

Work Authorization

Applicants must be authorized to work in the United States without the need for current or future sponsorship.

Pre-Employment Requirements

Employment is contingent upon successful completion of a background check, reference checks and pre-employment drug screening, where permitted by applicable law.  For certain roles, additional screenings such as a credit check or motor vehicle record review may be required, where job-related and consistent with business necessity.

Notice to Staffing Agencies and Third-Party Recruiters

Immatics US partners with a select group of approved staffing agencies. Candidate submissions are accepted only from agencies that have a current written agreement with Immatics US and signed and formally engaged by our Talent Acquisition team for an active search. Unsolicited resumes or candidate information, including submissions made directly to hiring managers, will not be considered and are not eligible for placement fees.