Scientist (52834)

Position Objective: The Scientist will provide support services to satisfy the overall operational objectives of the National Institute on Aging (NIA) within the National Institutes of Health.

Duties and Responsibilities:

- Evaluate new techniques, instruments, and software for potential incorporation into current SOP.

- Advance the science in the laboratory through new procedures and discoveries.

- Design and conduct experiments and studies requiring the application of a broad professional knowledge of scientific theories and principles.

- Work with staff on the interpretation of experiments performed by research scientists.

- Work with postdoc/biological scientists to perform statistical analysis for research projects.

- Work with staff on assay design and method development using an array or experimentation.

- Train staff on the proper usage of laboratory instruments and equipment.

- Calibrate, maintain and troubleshoot instruments and equipment in the laboratory.

- Operate, troubleshoot and train others to use laboratory equipment and software.

- Provide advice and assistance to users in designing experiments, using instrumentation, data acquisition and analysis, and preparing figures for publication.

- Submit and gain approval of laboratory animal study protocols.

- Utilize scientific equipment and resources (e.g. reagents, stocks of frozen sells, animal samples) including acquisition, documentation and storage.

- Participate in the laboratorys review of future proposals for resource allocations.

- Write technical reports and prepare manuscripts.

- Conduct bioinformatics data analyses and statistical analyses; prepare data for abstracts and manuscripts.

- Maintain a detailed and up-to-date electronic laboratory notebook detailing all experiments.

- Work with staff to confirm assay results and evaluate new techniques and instruments; search literature; propose, design and test

- alternative assays for difficult screening targets; confirm assay results; develop secondary assays.

- Work with Principal Investigators in scheduling and prioritizing instrument usage.

- Coordinate with IT staff on all software issues specific to the chemistry group and on all computer problems.

- Participate in establishing criteria and standards for others to follow in the planning, review and evaluation of bioinformatics research projects.

- Prepare oral presentations and posters for internal and external groups/conferences.

- Co-author manuscripts on research projects; publish in peer-reviewed journals.

- Write papers and abstracts detailing research efforts and results for publication in peer-reviewed journals; prepare PowerPoint presentations as appropriate.

- Give posters and presentations detailing work at regional and national scientific meetings.

- Review, edit, and, as needed, write first drafts of papers, posters and manuscripts.

- Give posters and presentations detailing work at regional and national scientific meetings.

- Present results of clinical and experimental research at recognized scientific meetings by lectures and exhibits (poster sessions).

- Provides interpretation of results, guidance, and scientific support to the management team.

- Search existing literature for new and/or relevant techniques.

- Assist the lab staff in the creation and preparation of a variety of documents required by the labs scientific activities. 4

- Produce research reports and regularly communicate results to staff and collaborators. 5

- Prepare information for and attend review committee and panel meetings; respond to issues and concerns about specific applications/ proposal pertaining to assigned program area

- Train staff on the proper usage of equipment. 2

- Train staff in a wide variety of techniques used in the laboratory.

- Coordinate training of users in applying data and analysis methods for their research studies.

- Provide scientific and technical expertise to all visiting fellows, post-docs, and technicians. 1

- Train laboratory staff to independently run the experiments and analyze the data. 3

- Work with Section/Unit Investigators in training students and postdoctoral fellows in various research techniques used in laboratory section/unit, and in maintaining laboratory safety.

- Apply a wide range of conventional, established approaches, methods, techniques and solutions to new situations.

- Identify and recommend resolution of discrepancies; recommend or determine what data to use, record or report.

- Recommend and justify appropriate resource management strategies.

- Write and edit scientific papers.

- Operate and perform routine maintenance on laboratory instruments and equipment.

- Ensure that scientific supplies are kept stocked; obtain quotes and prepare purchase requests for supplies, instruments and equipment, and submit them to primary investigator and/or lab manager for approval.

- Perform various molecular biology techniques, including, but not limited to, RNA sequencing, real-time PCR, Western Blotting and protein analysis.

- Perform immunostaining and produce high-quality images using confocal microscopy to locate distribution of key proteins in cardiac myocytes and sinoatrial node cells.

- Perform cell culture and adenoviral transfection of cardiac myocytes and sinoatrial node cells.

- Perform various bioassay and radioimmunoassay.

- Prepare and maintain animal study protocols.

- Perform a variety of experiments, maintain an accurate research tracking system and database for all research activities; maintain and update accurate records of experiments and results, including research documentation.

- Submit summary of research activity to primary investigator weekly.

- Collect data, perform statistical analysis and prepare data and/or results for presentation and/ or publication.

- Perform data analysis for physiology and biochemical assays.

- Actively participate in weekly laboratory meetings by discussing data and/or results and present data and/or results and scientific papers.

- Collaborate with laboratory scientists and participate in planning and managing components of a wide array of research projects.

- Work products related to performing various molecular biology techniques, immunostaining, cell culture and adenoviral transfection; perform bioassays and radioimmunoassay; prepare and maintain animal study protocols.

- Work products and documents related to performing experiments; maintain research tracking system and database; maintain and update records of experiments and results; perform data analysis for physiology and biochemical assays.

- Work products and documents related to preparing summary of research activity; collect data; perform statistical analysis; prepare data and results for presentation and publication; participate in weekly laboratory meetings; present and discuss data and results.

- Work products and documents related to training students and fellows in research techniques; maintain laboratory safety; recommend and justify resource management strategies; write and edit scientific papers; operate and perform routine maintenance on instruments and equipment; maintain adequate stock of supplies.

- Clean Equipment, Inspect Equipment, and Meet with lab members to present updates

Qualifications

Basic Qualifications:

- Masters degree in Biotechnology or a related discipline

- Experience with histopathologic studies of cardiovascular and cerebrovascular remodeling in aging, as well as knowledge of cardiovascular diseases in both humans and animal models

- Skilled in NIH POTS, PowerPoint, and MS Office Suite

Preferred Qualifications:

- Ability to communicate effectively, orally and in writing, with non-technical and technical staff

- Detail-oriented and possess strong organizational skills with the ability to prioritize multiple tasks and projects

*This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required by this position.

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

GAP Solutions provides reasonable accommodations to qualified individuals with disabilities. If you need an accommodation to apply for a job, email us at [email protected] . You will need to reference the requisition number of the position in which you are interested. Your message will be routed to the appropriate recruiter who will assist you. Please note, this email address is only to be used for those individuals who need an accommodation to apply for a job. Emails for any other reason or those that do not include a requisition number will not be returned.

Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status or other characteristics protected by law.

This position is contingent upon contract award.